Interactor 1: PPARG (P37231)
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)
Gene: PPARG

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.620

The method score is based on:

Property Details
Experiments 21690289, 12813462
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0010628 - positive regulation of gene expression
GO:0010875 - positive regulation of cholesterol efflux
GO:0019899 - enzyme binding
GO:0030154 - cell differentiation
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 505
Hs

1 178
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024