HitPredict

Interactor 1: PPARG (P37231)
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)
Gene: PPARG

Interactor 2: TRIP4 (Q15650)
Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4)
Gene: TRIP4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19596656, 11500849
Identification Methods	unspecified method, fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 581
+	Hs
		587175 RXRA_HUMAN (21-502): 4.79e-118: 356: 23.22		TRIP4_HUMAN (1-581): 0: 959: 100.00
+	Hs
		369680 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		TRIP4_HUMAN (1-581): 0: 959: 100.00
+	Hs
		487976 RARA_HUMAN (45-503): 3.89e-102: 316: 25.22		TRIP4_HUMAN (1-581): 0: 959: 100.00
+	Hs
		622796 COT2_HUMAN (70-501): 3.99e-101: 311: 22.35		TRIP4_HUMAN (1-581): 0: 959: 100.00
+	Hs
		1076269 ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70		TRIP4_HUMAN (1-581): 0: 959: 100.00
+	Hs
		500489 THB_HUMAN (85-503): 3.83e-93: 292: 23.90		TRIP4_HUMAN (1-581): 0: 959: 100.00