HitPredict

Interactor 1: PPARG (P37231)
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)
Gene: PPARG

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	36737649, 36998980
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007165 - signal transduction GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 548
+	Hs
		740576 PPARG_HUMAN (1-505): 2.47e-165: 479: 100.00		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		992448 PPARA_HUMAN (31-505): 4.22e-120: 362: 54.18		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		740518 PPARG_HUMAN (1-505): 2.47e-165: 479: 100.00		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		536747 PPARG_HUMAN (1-505): 2.47e-165: 479: 100.00		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		242818 PPARG_HUMAN (1-505): 2.47e-165: 479: 100.00		TRI13_HUMAN (17-333): 3.8e-62: 211: 22.64
+	Hs
		992438 PPARA_HUMAN (31-505): 4.22e-120: 362: 54.18		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		262145 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		TRIM3_HUMAN (7-525): 5.4e-80: 267: 16.64
+	Hs
		369530 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		370719 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Hs
		369497 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		TRI26_HUMAN (12-339): 5.62e-65: 222: 16.23
+	Hs
		370380 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		TRIM8_HUMAN (18-465): 8.09e-65: 222: 18.25
+	Hs
		265849 NR1I2_HUMAN (139-501): 1.19e-104: 321: 26.26		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		368914 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		370187 ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28		TRI11_HUMAN (12-402): 5.69e-62: 212: 16.88
+	Hs
		377297 GCR_HUMAN (18-503): 1.99e-98: 315: 17.85		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		659746 RXRB_HUMAN (82-502): 6.79e-105: 325: 23.35		TRIM1_HUMAN (17-367): 3.2e-63: 222: 21.28
+	Hs
		536736 RXRB_HUMAN (82-502): 6.79e-105: 325: 23.35		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		818879 RXRG_HUMAN (15-502): 9.55e-118: 356: 22.97		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		659723 RXRB_HUMAN (82-502): 6.79e-105: 325: 23.35		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		377417 GCR_HUMAN (18-503): 1.99e-98: 315: 17.85		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39