HitPredict

Interactor 1: HPCL1 (P37235)
Hippocalcin-like protein 1 (Calcium-binding protein BDR-1) (HLP2) (Visinin-like protein 3) (VILIP-3)
Gene: HPCAL1

Interactor 2: SPRE1 (Q7Z699)
Sprouty-related, EVH1 domain-containing protein 1 (Spred-1) (hSpred1)
Gene: SPRED1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 444
+	Hs
		901310 NCALD_HUMAN (1-193): 1.87e-58: 183: 90.67		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		917031 VISL1_HUMAN (1-189): 2.45e-49: 160: 67.02		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		1191592 KCIP2_HUMAN (4-188): 3.14e-48: 159: 40.54		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		1191628 HPCL4_HUMAN (1-189): 4.96e-49: 159: 66.49		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		1191414 KCIP1_HUMAN (9-188): 9.48e-52: 167: 43.33		SPRE2_HUMAN (1-444): 1.36e-148: 430: 50.44
+	Hs
		917030 VISL1_HUMAN (1-189): 2.45e-49: 160: 67.02		SPRE2_HUMAN (1-444): 1.36e-148: 430: 50.44
+	Hs
		906770 NCS1_HUMAN (1-187): 1.82e-47: 155: 59.89		SPRE2_HUMAN (1-444): 1.36e-148: 430: 50.44
+	Hs
		208415 VISL1_HUMAN (1-189): 2.45e-49: 160: 67.02		SPY3_HUMAN (201-435): 5.31e-43: 154: 16.79