HitPredict

Interactor 1: HPCL1 (P37235)
Hippocalcin-like protein 1 (Calcium-binding protein BDR-1) (HLP2) (Visinin-like protein 3) (VILIP-3)
Gene: HPCAL1

Interactor 2: DTX2 (Q86UW9)
Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2)
Gene: DTX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.633

Property	Details
Experiments	16189514, 32296183, 35198878, unassigned1304
Identification Methods	two hybrid, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 622
+	Hs
		901312 NCALD_HUMAN (1-193): 1.87e-58: 183: 90.67		DTX2_HUMAN (1-622): 0: 572: 100.00
+	Hs
		950458 HPCA_HUMAN (1-193): 6.75e-58: 182: 94.30		DTX2_HUMAN (1-622): 0: 572: 100.00
+	Hs
		917033 VISL1_HUMAN (1-189): 2.45e-49: 160: 67.02		DTX2_HUMAN (1-622): 0: 572: 100.00
+	Hs
		1200374 HPCL4_HUMAN (1-189): 4.96e-49: 159: 66.49		DTX2_HUMAN (1-622): 0: 572: 100.00
+	Hs
		906771 NCS1_HUMAN (1-187): 1.82e-47: 155: 59.89		DTX2_HUMAN (1-622): 0: 572: 100.00
+	Hs
		740703 HPCL1_HUMAN (1-193): 1.55e-60: 188: 100.00		DTX4_HUMAN (17-622): 1.71e-150: 449: 43.36