HitPredict

Interactor 1: ZEB1 (P37275)
Zinc finger E-box-binding homeobox 1 (NIL-2-A zinc finger protein) (Negative regulator of IL2) (Transcription factor 8) (TCF-8)
Gene: ZEB1

Interactor 2: CTBP2 (P56545)
C-terminal-binding protein 2 (CtBP2)
Gene: CTBP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.729

The method score is based on:

Property Details
Experiments 25086746, 34462429, 10567582, 10359772, 35271311, 19754958
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0045892 - negative regulation of DNA-templated transcription
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1124
Hs

1 445
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Last updated: 15 Jul 2024