HitPredict

Interactor 1: VRP1 (P37370)
Verprolin
Gene: VRP1

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.893

Property	Details
Experiments	9412475, 10358064, 17635585, 11742975
Identification Methods	two hybrid, far western blotting, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0006897 - endocytosis GO:0030479 - actin cortical patch
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 817 Sc			1 375
+	Hs
		554315 MUC1_HUMAN (52-810): 3.67e-45: 177: 11.30		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Hs
		554290 MUC1_HUMAN (52-810): 3.67e-45: 177: 11.30		ACTA_HUMAN (2-375): 0: 589: 86.63
+	Hs
		1122431 SRCAP_HUMAN (191-817): 3.96e-12: 72.4: 9.73		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Hs
		932156 MDC1_HUMAN (23-817): 1.05e-25: 116: 10.81		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		891853 SRCAP_HUMAN (191-817): 3.96e-12: 72.4: 9.73		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Dm
		501445 CPN_DROME (376-816): 6.79e-14: 77.8: 12.90		ACT5_DROME (2-375): 0: 595: 88.50
+	Hs
		929905 SRCAP_HUMAN (191-817): 3.96e-12: 72.4: 9.73		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Dm
		501503 Q86BH2_DROME (29-797): 4.21e-11: 69.3: 9.36		ACT1_DROME (2-375): 0: 596: 89.31
+	Hs
		932219 SRCAP_HUMAN (191-817): 3.96e-12: 72.4: 9.73		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		932341 CIC_HUMAN (10-707): 1.45e-10: 67.4: 13.59		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		203220 SYNJ1_HUMAN (63-493): 8.24e-10: 65.1: 11.49		ACTC_HUMAN (2-375): 0: 591: 87.17