HitPredict

Interactor 1: TAGL2 (P37802)
Transgelin-2 (Epididymis tissue protein Li 7e) (SM22-alpha homolog)
Gene: TAGLN2

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 199 Hs			1 375
+	Hs
		741850 TAGL2_HUMAN (1-199): 1.65e-87: 257: 100.00		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		741856 TAGL2_HUMAN (1-199): 1.65e-87: 257: 100.00		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		891782 CNN3_HUMAN (3-198): 1.27e-77: 237: 43.37		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		891988 CNN2_HUMAN (3-198): 1.69e-74: 228: 40.31		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		932175 CNN3_HUMAN (3-198): 1.27e-77: 237: 43.37		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		932344 CNN2_HUMAN (3-198): 1.69e-74: 228: 40.31		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Rn
		933100 CNN1_RAT (3-198): 7.04e-75: 229: 42.35		ACTS_RAT (2-375): 0: 594: 93.85
+	Hs
		851163 CNN1_HUMAN (3-198): 7.89e-74: 226: 42.86		ACTS_HUMAN (2-375): 0: 594: 93.85
+	Dm
		862565 Q9I7J0_DROME (22-198): 5.75e-61: 189: 35.03		ACT3_DROME (2-375): 0: 596: 94.92
+	Hs
		809232 IQGA1_HUMAN (4-181): 5.8e-46: 163: 17.99		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		809257 IQGA1_HUMAN (4-181): 5.8e-46: 163: 17.99		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		891748 IQGA2_HUMAN (4-181): 4.11e-45: 161: 16.93		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Sc
		887705 SCP1_YEAST (4-199): 1.16e-52: 169: 32.18		ACT_YEAST (1-375): 0: 592: 89.07
+	Sp
		144980 IQG1_SCHPO (4-158): 4.21e-38: 141: 18.71		ACT_SCHPO (1-375): 0: 594: 91.47
+	Sc
		887718 IQG1_YEAST (7-169): 1.15e-32: 125: 20.00		ACT_YEAST (1-375): 0: 592: 89.07
+	Hs
		933037 LRCH3_HUMAN (2-143): 2.63e-31: 121: 19.31		ACTS_HUMAN (2-375): 0: 594: 93.85
+	Hs
		892114 LIMC1_HUMAN (29-138): 3.62e-13: 69.3: 24.59		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		891926 LMO7_HUMAN (34-153): 4.13e-13: 68.9: 24.24		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		932285 LMO7_HUMAN (34-153): 4.13e-13: 68.9: 24.24		ACTC_HUMAN (2-375): 0: 595: 94.39