HitPredict

Interactor 1: NOP4 (P37838)
Nucleolar protein 4 (Nucleolar protein NOP77)
Gene: NOP4

Interactor 2: NOP15 (P53927)
Ribosome biogenesis protein 15 (Nucleolar protein 15)
Gene: NOP15

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	11805826, 16429126, 17922018, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005634 - nucleus GO:0005730 - nucleolus GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 685 Sc			1 220
+	Sc
		376645 PABP_YEAST (11-296): 5.45e-43: 165: 18.88		RNA15_YEAST (85-166): 6.34e-13: 68.3: 21.95
+	Hs
		198898 ELAV1_HUMAN (405-633): 5.09e-16: 81.7: 13.42		RFOX2_HUMAN (19-183): 1.37e-35: 131: 19.88
+	Hs
		516484 PABP1_HUMAN (3-143): 4.72e-20: 96.7: 19.15		ELAV2_HUMAN (2-173): 1.13e-29: 114: 13.48
+	Zm
		8143 A0A1D6ELH4_MAIZE (3-186): 5.47e-24: 109: 16.04		A0A1D6ELH4_MAIZE (60-207): 6.71e-23: 98.1: 14.19
+	Hs
		703388 ELAV1_HUMAN (405-633): 5.09e-16: 81.7: 13.42		CSTF2_HUMAN (91-193): 1.45e-32: 125: 22.22
+	Hs
		1020259 ELAV3_HUMAN (489-640): 1.51e-18: 89.8: 11.84		ELAV2_HUMAN (2-173): 1.13e-29: 114: 13.48
+	Hs
		516339 PABP1_HUMAN (3-143): 4.72e-20: 96.7: 19.15		PABP1_HUMAN (82-207): 1.24e-25: 105: 15.87
+	Hs
		516495 PABP1_HUMAN (3-143): 4.72e-20: 96.7: 19.15		PABP4_HUMAN (89-207): 3.83e-25: 104: 17.65
+	Hs
		1020265 ELAV1_HUMAN (405-633): 5.09e-16: 81.7: 13.42		ELAV2_HUMAN (2-173): 1.13e-29: 114: 13.48
+	Hs
		516471 PABP1_HUMAN (3-143): 4.72e-20: 96.7: 19.15		TIAR_HUMAN (85-207): 2.06e-23: 98.1: 17.89
+	Hs
		516689 PABP1_HUMAN (3-143): 4.72e-20: 96.7: 19.15		PABP3_HUMAN (82-207): 9.87e-23: 97.4: 17.46
+	Mm
		665745 PABP1_MOUSE (3-143): 5.02e-20: 96.7: 19.15		TIA1_MOUSE (86-216): 1.37e-21: 93.1: 18.80
+	Hs
		516730 PABP1_HUMAN (3-143): 4.72e-20: 96.7: 19.15		PUF60_HUMAN (11-173): 8.5e-21: 91.8: 20.83
+	Hs
		1031344 ELAV1_HUMAN (405-633): 5.09e-16: 81.7: 13.42		PABP4_HUMAN (89-207): 3.83e-25: 104: 17.65
+	Hs
		1077376 ELAV1_HUMAN (405-633): 5.09e-16: 81.7: 13.42		ELAV1_HUMAN (85-207): 6.15e-25: 101: 18.70
+	Hs
		963526 ELAV1_HUMAN (405-633): 5.09e-16: 81.7: 13.42		TIAR_HUMAN (85-207): 2.06e-23: 98.1: 17.89
+	Mm
		936687 ELAV1_MOUSE (405-633): 5.53e-16: 81.7: 12.55		Q80ZW7_MOUSE (86-207): 2.66e-23: 97.8: 19.67
+	Hs
		680455 ELAV1_HUMAN (405-633): 5.09e-16: 81.7: 13.42		TIA1_HUMAN (86-216): 1.35e-21: 93.1: 18.80
+	Mm
		857310 ELAV1_MOUSE (405-633): 5.53e-16: 81.7: 12.55		TIA1_MOUSE (86-216): 1.37e-21: 93.1: 18.80