HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: SC6A3 (Q01959)
Sodium-dependent dopamine transporter (DA transporter) (DAT) (Solute carrier family 6 member 3)
Gene: SLC6A3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

The method score is based on:

Property	Details
Experiments	12672538, 11292651, 14550771, 14756560, 16216085, 22163275
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0009410 - response to xenobiotic stimulus GO:0016020 - membrane GO:0030424 - axon and 4 others more... GO:0042416 - dopamine biosynthetic process GO:0043025 - neuronal cell body GO:0043679 - axon terminus GO:0051583 - dopamine uptake involved in synaptic transmission
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	140
Hs

1	620

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024