HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: GRK1 (Q15835)
Rhodopsin kinase GRK1 (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)
Gene: GRK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10852916
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 563
+	Hs
		742110 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		GRK6_HUMAN (5-559): 5.95e-171: 498: 46.76
+	Hs
		714489 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		GRK5_HUMAN (5-559): 2.26e-167: 489: 45.68
+	Hs
		1079321 SYUB_HUMAN (1-126): 2.84e-36: 122: 58.02		GRK1_HUMAN (1-563): 1.18e-179: 519: 100.00
+	Hs
		282779 SYUG_HUMAN (1-100): 1.25e-28: 103: 66.00		GRK1_HUMAN (1-563): 1.18e-179: 519: 100.00
+	Hs
		794388 SYUB_HUMAN (1-126): 2.84e-36: 122: 58.02		GRK6_HUMAN (5-559): 5.95e-171: 498: 46.76
+	Hs
		714539 SYUB_HUMAN (1-126): 2.84e-36: 122: 58.02		GRK5_HUMAN (5-559): 2.26e-167: 489: 45.68
+	Hs
		626629 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		ARBK1_HUMAN (3-548): 1.3e-141: 427: 31.84
+	Hs
		282772 SYUG_HUMAN (1-100): 1.25e-28: 103: 66.00		GRK6_HUMAN (5-559): 5.95e-171: 498: 46.76
+	Hs
		681700 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		AKT1_HUMAN (76-524): 1.09e-141: 420: 25.38
+	Hs
		282769 SYUG_HUMAN (1-100): 1.25e-28: 103: 66.00		GRK5_HUMAN (5-559): 2.26e-167: 489: 45.68
+	Hs
		742230 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		KPCE_HUMAN (54-512): 2.3e-137: 417: 26.43
+	Hs
		681868 SYUB_HUMAN (1-126): 2.84e-36: 122: 58.02		AKT1_HUMAN (76-524): 1.09e-141: 420: 25.38
+	Hs
		742241 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		KPCD_HUMAN (190-478): 4.52e-63: 221: 41.03
+	Hs
		566312 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		KPCA_HUMAN (195-474): 5.31e-56: 201: 40.43