HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 19878656, 23183827
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000149 - SNARE binding
GO:0000287 - magnesium ion binding
GO:0003779 - actin binding
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
and 12 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 140
Hs

1 2527
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024