HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: HS105 (Q92598)
Heat shock protein 105 kDa (Antigen NY-CO-25) (Heat shock 110 kDa protein) (Heat shock protein family H member 1)
Gene: HSPH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex and 1 others more... GO:0043014 - alpha-tubulin binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 858
+	Hs
		320823 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		HS74L_HUMAN (1-858): 0: 953: 57.46
+	Hs
		714118 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		HSP74_HUMAN (1-858): 0: 917: 60.98
+	Rn
		291982 SYUA_RAT (1-140): 2.23e-57: 176: 95.00		HSP74_RAT (1-858): 0: 914: 61.28
+	Hs
		503576 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		HSP7C_HUMAN (489-709): 2.48e-32: 135: 11.26
+	Rn
		741578 SYUA_RAT (1-140): 2.23e-57: 176: 95.00		HSP7C_RAT (489-709): 5.46e-32: 134: 11.26
+	Hs
		713917 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		HS71L_HUMAN (586-716): 7.63e-31: 131: 19.70