HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: SEPT5 (Q99719)
Septin-5 (Cell division control-related protein 1) (CDCrel-1) (Peanut-like protein 1)
Gene: SEPTIN5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36634849
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0060090 - molecular adaptor activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 369
+	Hs
		198182 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		SEPT4_HUMAN (14-368): 0: 523: 76.92
+	Rn
		741612 SYUA_RAT (1-140): 2.23e-57: 176: 95.00		SEPT7_RAT (2-368): 2.05e-173: 491: 49.09
+	Hs
		742320 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		SEPT7_HUMAN (2-368): 5.44e-173: 490: 48.83
+	Hs
		742300 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		SEPT2_HUMAN (7-361): 6.92e-171: 482: 57.75
+	Hs
		742562 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		SEP11_HUMAN (10-358): 6.34e-164: 467: 38.98
+	Hs
		742584 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		SEPT9_HUMAN (8-329): 1.2e-158: 459: 45.20
+	Hs
		742582 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		SEPT3_HUMAN (8-333): 1.1e-158: 451: 45.62