Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: SNCAP (Q9Y6H5)
Synphilin-1 (Sph1) (Alpha-synuclein-interacting protein)
Gene: SNCAIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.761

The method score is based on:

Property Details
Experiments 12044636, 11331421, 10319874, 15944382, 15894486, 14645218, 16365047, 25861987, 11742726, 19762560, 16595633
Identification Methods two hybrid, fluorescent resonance energy transfer, affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation, nuclear magnetic resonance, cross-linking study, fluorescence correlation spectroscopy
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043025 - neuronal cell body
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 140
Hs

1 919
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024