HitPredict

Interactor 1: AKL1 (P38080)
Serine/threonine-protein kinase AKL1 (EC 2.7.11.1)
Gene: AKL1

Interactor 2: UBP5 (P39944)
Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.4.19.12) (Deubiquitinating enzyme 5) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5)
Gene: UBP5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.762

Property	Details
Experiments	10688190, 11283351
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Pkinase~Rhodanese
Common GO terms	GO:0005935 - cellular bud neck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1108 Sc			1 805
+	Sc
		765454 PRK1_YEAST (14-668): 3.32e-99: 334: 29.17		UBP5_YEAST (1-805): 0: 899: 100.00
+	Hs
		1183143 MARK2_HUMAN (8-759): 9.36e-118: 384: 16.10		UBP21_HUMAN (275-804): 4.92e-111: 351: 24.41
+	Hs
		647975 MARK3_HUMAN (2-759): 4.2e-116: 378: 16.41		UBP21_HUMAN (275-804): 4.92e-111: 351: 24.41
+	Hs
		681706 AKT1_HUMAN (1-373): 1.19e-112: 360: 16.54		UBP8_HUMAN (337-801): 1.05e-109: 363: 27.87
+	Hs
		1183139 MARK2_HUMAN (8-759): 9.36e-118: 384: 16.10		UBP36_HUMAN (376-804): 7.42e-91: 311: 22.97
+	Hs
		681912 AKT1_HUMAN (1-373): 1.19e-112: 360: 16.54		UBP50_HUMAN (445-765): 7.69e-30: 123: 29.76
+	Hs
		1024411 SLK_HUMAN (9-1047): 5.81e-115: 387: 13.98		UBP4_HUMAN (623-803): 9.81e-19: 93.6: 33.69
+	Hs
		1329548 TAOK3_HUMAN (35-793): 8.14e-116: 381: 16.77		UBP15_HUMAN (623-803): 8.52e-17: 87.4: 31.35
+	Hs
		681819 AKT1_HUMAN (1-373): 1.19e-112: 360: 16.54		UBP4_HUMAN (623-803): 9.81e-19: 93.6: 33.69