HitPredict

Interactor 1: MAK5 (P38112)
ATP-dependent RNA helicase MAK5 (EC 3.6.4.13) (Maintenance of killer protein 5)
Gene: MAK5

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 773 Sc			1 291
+	Sc
		733806 MAK5_YEAST (1-773): 3.79e-163: 493: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		624185 DBP2_YEAST (62-611): 3.49e-122: 379: 21.62		BRX1_YEAST (1-291): 1.12e-99: 295: 100.00
+	Sc
		744189 MAK5_YEAST (1-773): 3.79e-163: 493: 100.00		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Sc
		744188 MAK5_YEAST (1-773): 3.79e-163: 493: 100.00		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Sc
		415968 DED1_YEAST (146-611): 4.99e-117: 367: 25.31		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Sc
		699739 DRS1_YEAST (174-666): 9.19e-41: 162: 29.06		BRX1_YEAST (1-291): 1.12e-99: 295: 100.00
+	Sc
		976876 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		BRX1_YEAST (1-291): 1.12e-99: 295: 100.00
+	Hs
		1326334 DDX24_HUMAN (242-734): 2.14e-67: 241: 33.13		SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87
+	Sc
		699670 DRS1_YEAST (174-666): 9.19e-41: 162: 29.06		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		733917 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		866605 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		IMP4_YEAST (5-261): 1.73e-61: 198: 17.76
+	Sc
		753163 DBP8_YEAST (178-619): 1.57e-39: 153: 29.33		IMP4_YEAST (5-261): 1.73e-61: 198: 17.76
+	Sc
		699680 DRS1_YEAST (174-666): 9.19e-41: 162: 29.06		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Sc
		755323 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Hs
		1292660 DDX27_HUMAN (57-587): 1.9e-39: 158: 28.55		SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87
+	Hs
		1343143 DDX18_HUMAN (70-598): 3.25e-38: 153: 29.16		SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87
+	Sc
		699679 DRS1_YEAST (174-666): 9.19e-41: 162: 29.06		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Sc
		699748 DRS1_YEAST (174-666): 9.19e-41: 162: 29.06		SSF2_YEAST (10-197): 8.32e-33: 127: 15.17
+	Sc
		754899 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Sc
		976889 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		SSF2_YEAST (10-197): 8.32e-33: 127: 15.17