Interactor 1: MAK5 (P38112)
ATP-dependent RNA helicase MAK5 (EC 3.6.4.13) (Maintenance of killer protein 5)
Gene: MAK5

Interactor 2: DBP10 (Q12389)
ATP-dependent RNA helicase DBP10 (EC 3.6.4.13) (DEAD box protein 10)
Gene: DBP10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.899

The method score is based on:

Property Details
Experiments 16449635, 25877921, 30568249, unassigned1262
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, Helicase_C~Helicase_C
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 773
Sc

1 995
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Dm

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Last updated: 15 Jul 2024