HitPredict

Interactor 1: SWD3 (P38123)
COMPASS component SWD3 (Complex proteins associated with SET1 protein SWD3) (Set1C component SWD3)
Gene: SWD3

Interactor 2: KOG1 (P38873)
Target of rapamycin complex 1 subunit KOG1 (TORC1 subunit KOG1) (Kontroller of growth protein 1) (Local anesthetic-sensitive protein 24) (Regulatory-associated protein of TOR) (Raptor)
Gene: KOG1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 315 Sc			1 1557
+	Sc
		561870 TUP1_YEAST (89-312): 1.66e-20: 93.9: 17.16		KOG1_YEAST (1-1557): 0: 1428: 100.00
+	Hs
		903349 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		WDR5B_HUMAN (1108-1430): 3.23e-64: 223: 11.64
+	Hs
		863508 FBXW7_HUMAN (1-308): 2.78e-72: 237: 18.91		COPA_HUMAN (1199-1484): 2.15e-25: 117: 12.18
+	Hs
		792949 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		LIS1_HUMAN (1348-1552): 7.62e-38: 149: 9.80
+	Hs
		1240442 POC1B_HUMAN (40-311): 9.25e-73: 233: 21.82		POC1A_HUMAN (1142-1317): 1.14e-18: 92.3: 11.74
+	Hs
		903418 FBXW7_HUMAN (1-308): 2.78e-72: 237: 18.91		WDR5_HUMAN (1043-1284): 1.48e-16: 85: 9.31
+	Hs
		1103007 FBXW7_HUMAN (1-308): 2.78e-72: 237: 18.91		SMU1_HUMAN (1267-1548): 4.52e-12: 72.6: 16.83
+	Hs
		863397 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		COPA_HUMAN (1199-1484): 2.15e-25: 117: 12.18
+	Sp
		999842 TUP12_SCHPO (87-312): 1.26e-47: 170: 21.37		TUP11_SCHPO (1334-1553): 3.25e-28: 124: 12.55
+	Sp
		999838 TUP11_SCHPO (121-312): 7.57e-41: 151: 19.07		TUP11_SCHPO (1334-1553): 3.25e-28: 124: 12.55
+	Hs
		903077 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		WDR5_HUMAN (1043-1284): 1.48e-16: 85: 9.31
+	Hs
		725410 WDR5_HUMAN (4-216): 3.22e-55: 184: 19.09		COPB2_HUMAN (1125-1282): 7.75e-11: 69.2: 14.56
+	Hs
		196984 PRP4_HUMAN (94-313): 5.33e-43: 156: 13.97		WDR5_HUMAN (1043-1284): 1.48e-16: 85: 9.31
+	Dm
		1358859 FBXW7_DROME (2-162): 2.48e-30: 122: 18.61		WDS_DROME (1111-1287): 1.33e-17: 88.4: 9.89
+	Hs
		903428 SNR40_HUMAN (168-313): 8.85e-25: 103: 15.33		WDR5_HUMAN (1043-1284): 1.48e-16: 85: 9.31
+	Hs
		1102987 SMU1_HUMAN (136-314): 1.52e-24: 105: 21.23		SMU1_HUMAN (1267-1548): 4.52e-12: 72.6: 16.83
+	Sc
		561841 TUP1_YEAST (89-312): 1.66e-20: 93.9: 17.16		TUP1_YEAST (1267-1526): 3.96e-10: 66.8: 18.25