HitPredict

Interactor 1: MCM7 (P38132)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (Cell division control protein 47) (Minichromosome maintenance protein 7)
Gene: MCM7

Interactor 2: MCM6 (P53091)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (Minichromosome maintenance protein 6)
Gene: MCM6

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 28191893, 25172955, 17895243, 32804080, 35296675, 37968396, 22421151
Identification Methods pull down, affinity chromatography technology, biochemical, two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM6_C, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM6_C~MCM_lid, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 16 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 845
Sc

1 1017
+ Sc
+ Hs
+ Sc
+ Sp
+ At
+ Sc
+ Xl
+ Hs
+ Sp
+ Hs
+ Hs
+ Mm
+ Hs
+ Xl
+ Sp
+ Xl
+ Xl
+ Sp
+ Hs
+ Xl

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Last updated: 15 Jul 2024