HitPredict

Interactor 1: ISW1 (P38144)
ISWI chromatin-remodeling complex ATPase ISW1 (EC 3.6.4.-)
Gene: ISW1

Interactor 2: RSC4 (Q02206)
Chromatin structure-remodeling complex subunit RSC4 (RSC complex subunit RSC4) (Remodel the structure of chromatin complex subunit 4)
Gene: RSC4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.657

Property	Details
Experiments	11805826, 16429126, 21179020
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1129 Sc			1 625
+	Sc
		969433 ISW2_YEAST (19-1108): 0: 803: 46.97		RSC4_YEAST (1-625): 0: 597: 100.00
+	Hs
		229448 SMCA5_HUMAN (86-1094): 0: 869: 46.69		PHIP_HUMAN (16-470): 3.23e-64: 232: 15.67
+	Sc
		744901 ISW1_YEAST (1-1129): 0: 932: 100.00		GCN5_YEAST (5-160): 4.11e-20: 95.3: 16.77
+	Hs
		1255033 CHD5_HUMAN (45-1127): 0: 782: 25.58		PHIP_HUMAN (16-470): 3.23e-64: 232: 15.67
+	Sc
		744916 ISW1_YEAST (1-1129): 0: 932: 100.00		RSC2_YEAST (55-196): 1.71e-13: 76.1: 19.01
+	Dm
		1097647 ISWI_DROME (72-1111): 0: 851: 43.95		NU301_DROME (193-290): 2.79e-29: 126: 34.65
+	Hs
		1199209 CHD7_HUMAN (25-1127): 0: 804: 26.50		PB1_HUMAN (24-312): 2.23e-43: 169: 18.37
+	Hs
		229482 SMCA5_HUMAN (86-1094): 0: 869: 46.69		CECR2_HUMAN (15-187): 1.05e-19: 96.2: 13.04
+	Hs
		658726 SMCA1_HUMAN (70-1079): 0: 869: 46.98		CECR2_HUMAN (15-187): 1.05e-19: 96.2: 13.04
+	Hs
		229252 SMCA5_HUMAN (86-1094): 0: 869: 46.69		BRD4_HUMAN (79-180): 1.04e-11: 70.2: 19.05
+	Hs
		243979 SMCA1_HUMAN (70-1079): 0: 869: 46.98		BRD4_HUMAN (79-180): 1.04e-11: 70.2: 19.05
+	Hs
		319278 CHD5_HUMAN (45-1127): 0: 782: 25.58		BRD1_HUMAN (20-204): 3.2e-23: 106: 17.44
+	Mm
		57185 CHD7_MOUSE (25-1127): 0: 808: 26.50		SMCA4_MOUSE (56-148): 2.07e-12: 72.8: 33.33
+	Hs
		847103 CHD7_HUMAN (25-1127): 0: 804: 26.50		SMCA4_HUMAN (56-148): 3.01e-12: 72.1: 33.00
+	Hs
		319179 CHD3_HUMAN (45-1120): 0: 770: 25.63		BRD1_HUMAN (20-204): 3.2e-23: 106: 17.44
+	Hs
		998619 CHD3_HUMAN (45-1120): 0: 770: 25.63		EP300_HUMAN (4-210): 2.62e-21: 101: 14.35
+	Hs
		600135 CHD3_HUMAN (45-1120): 0: 770: 25.63		TAF1_HUMAN (128-301): 1.03e-20: 99.6: 12.57
+	Hs
		846950 CHD3_HUMAN (45-1120): 0: 770: 25.63		SMCA4_HUMAN (56-148): 3.01e-12: 72.1: 33.00
+	Hs
		846763 CHD3_HUMAN (45-1120): 0: 770: 25.63		SMCA2_HUMAN (78-148): 9.33e-12: 70.5: 34.72
+	Hs
		244356 CHD3_HUMAN (45-1120): 0: 770: 25.63		BRD4_HUMAN (79-180): 1.04e-11: 70.2: 19.05