HitPredict

Interactor 1: ISW1 (P38144)
ISWI chromatin-remodeling complex ATPase ISW1 (EC 3.6.4.-)
Gene: ISW1

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	19106085, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1129 Sc			1 134
+	Sc
		392106 ISW1_YEAST (1-1129): 0: 932: 100.00		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392403 ISW1_YEAST (1-1129): 0: 932: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		229433 SMCA5_HUMAN (86-1094): 0: 869: 46.69		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		229286 SMCA5_HUMAN (86-1094): 0: 869: 46.69		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		469951 SMCA1_HUMAN (70-1079): 0: 869: 46.98		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		229279 SMCA5_HUMAN (86-1094): 0: 869: 46.69		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Sc
		996427 ISW2_YEAST (19-1108): 0: 803: 46.97		H2AZ_YEAST (1-134): 2.81e-53: 165: 100.00
+	Sc
		392595 ISW2_YEAST (19-1108): 0: 803: 46.97		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		1018640 CHD3_HUMAN (45-1120): 0: 770: 25.63		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		1059647 CHD4_HUMAN (45-1127): 0: 751: 25.91		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Hs
		1059717 CHD4_HUMAN (45-1127): 0: 751: 25.91		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		1059795 CHD4_HUMAN (45-1127): 0: 751: 25.91		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		470170 CHD8_HUMAN (18-1116): 0: 761: 26.01		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		470021 CHD4_HUMAN (45-1127): 0: 751: 25.91		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		391675 CHD3_HUMAN (45-1120): 0: 770: 25.63		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391915 CHD8_HUMAN (18-1116): 0: 761: 26.01		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391704 CHD4_HUMAN (45-1127): 0: 751: 25.91		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391728 CHD9_HUMAN (18-1054): 0: 743: 26.16		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Mm
		470232 SMCA4_MOUSE (128-942): 0: 711: 32.66		H2AZ_MOUSE (10-134): 6.73e-41: 134: 67.72
+	Hs
		469971 SMCA4_HUMAN (128-942): 0: 709: 31.43		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72