HitPredict

Interactor 1: CHK1 (P38147)
Serine/threonine-protein kinase CHK1 (EC 2.7.11.1) (Checkpoint kinase 1)
Gene: CHK1

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.798

Property	Details
Experiments	11805837, 14660704
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 527 Sc			1 375
+	Rn
		88697 AAPK1_RAT (4-510): 2.72e-125: 379: 21.25		D3ZRN3_RAT (1-375): 0: 686: 83.47
+	Hs
		681764 AKT1_HUMAN (1-349): 4.34e-122: 368: 22.60		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Rn
		871246 AAPK1_RAT (4-510): 2.72e-125: 379: 21.25		ACTS_RAT (2-375): 0: 590: 86.90
+	Hs
		681780 AKT1_HUMAN (1-349): 4.34e-122: 368: 22.60		ACTS_HUMAN (2-375): 0: 590: 86.90