HitPredict

Interactor 1: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0048025 - negative regulation of mRNA splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 391 Hs			1 344
+	Hs
		745150 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22
+	Hs
		992876 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65
+	Hs
		745135 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47
+	Hs
		993796 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47
+	Hs
		1029031 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		1028634 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22
+	Mm
		857324 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		Q542V3_MOUSE (1-343): 1.15e-52: 182: 51.93
+	Hs
		993869 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47
+	Mm
		857340 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		SRSF1_MOUSE (3-188): 3.02e-54: 180: 36.65
+	Hs
		1028873 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25
+	Hs
		1029160 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00
+	Hs
		474019 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PAB4L_HUMAN (1-196): 1.97e-35: 134: 15.94
+	Hs
		516389 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		745125 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Hs
		952076 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Hs
		516744 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Hs
		952176 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Hs
		951962 CIRBP_HUMAN (4-144): 1.3e-31: 119: 46.00		SRSF3_HUMAN (3-78): 2.4e-09: 57.4: 46.84
+	Hs
		516484 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PABP1_HUMAN (101-191): 1.28e-11: 67.6: 19.79
+	Mm
		665745 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		PABP1_MOUSE (101-191): 1.39e-11: 67.6: 19.79