HitPredict

Interactor 1: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Interactor 2: CIRBP (Q14011)
Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)
Gene: CIRBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	25416956, 16189514
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0048026 - positive regulation of mRNA splicing, via spliceosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 172
+	Hs
		745126 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		483438 RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74		CIRBP_HUMAN (1-172): 1.12e-39: 134: 100.00
+	Hs
		516389 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		PABP1_HUMAN (7-162): 4.32e-26: 105: 18.59
+	Hs
		483437 RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74		RBM3_HUMAN (1-166): 4.5e-33: 116: 54.22
+	Hs
		745259 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RMXL1_HUMAN (2-86): 1.01e-18: 83.6: 62.35
+	Hs
		745080 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBMX_HUMAN (2-86): 3.45e-18: 82: 62.35
+	Hs
		483431 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBY1A_HUMAN (2-118): 7.64e-16: 75.9: 51.28
+	Hs
		62458 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBY1E_HUMAN (2-118): 7.79e-16: 75.9: 51.28
+	Hs
		745118 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		TRA2B_HUMAN (8-132): 2.95e-15: 73.2: 46.40
+	Hs
		745179 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBY1F_HUMAN (2-118): 1.22e-14: 72.4: 49.57
+	Hs
		745100 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		ROA3_HUMAN (7-92): 2.98e-14: 70.9: 43.02
+	Hs
		483430 RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74		RBY1A_HUMAN (2-118): 7.64e-16: 75.9: 51.28
+	Hs
		483440 RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74		RBY1F_HUMAN (2-118): 1.22e-14: 72.4: 49.57
+	Hs
		62459 RBY1E_HUMAN (1-388): 1.16e-33: 132: 49.74		RBY1F_HUMAN (2-118): 1.22e-14: 72.4: 49.57