HitPredict

Interactor 1: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Interactor 2: RBY1F (Q15415)
RNA-binding motif protein, Y chromosome, family 1 member F/J (Y chromosome RNA recognition motif 2)
Gene: RBMY1F

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0048026 - positive regulation of mRNA splicing, via spliceosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 496
+	Hs
		483431 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBY1A_HUMAN (1-496): 5.7e-68: 227: 99.19
+	Hs
		62458 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBY1E_HUMAN (1-496): 9.26e-68: 227: 98.79
+	Hs
		483430 RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74		RBY1A_HUMAN (1-496): 5.7e-68: 227: 99.19
+	Hs
		483440 RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74		RBY1F_HUMAN (1-496): 1.01e-67: 227: 100.00
+	Hs
		62459 RBY1E_HUMAN (1-388): 1.16e-33: 132: 49.74		RBY1F_HUMAN (1-496): 1.01e-67: 227: 100.00
+	Hs
		745180 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		SAFB1_HUMAN (7-490): 1.87e-42: 163: 15.99
+	Hs
		745164 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		SAFB2_HUMAN (6-480): 1.25e-38: 152: 12.45
+	Hs
		745126 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBM3_HUMAN (4-90): 1.63e-25: 104: 50.00
+	Hs
		745162 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		CIRBP_HUMAN (4-146): 1.26e-24: 102: 40.14
+	Hs
		745080 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBMX_HUMAN (163-474): 8.04e-21: 96.1: 31.43
+	Hs
		745259 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RMXL1_HUMAN (236-465): 4.91e-17: 84.9: 38.36
+	Hs
		516389 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		PABP1_HUMAN (6-96): 5.64e-15: 79.6: 27.17
+	Hs
		483437 RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74		RBM3_HUMAN (4-90): 1.63e-25: 104: 50.00
+	Hs
		958194 RBY1F_HUMAN (1-388): 2.31e-33: 131: 49.74		RBM3_HUMAN (4-90): 1.63e-25: 104: 50.00
+	Hs
		483438 RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74		CIRBP_HUMAN (4-146): 1.26e-24: 102: 40.14