HitPredict

Interactor 1: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Interactor 2: SAFB1 (Q15424)
Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)
Gene: SAFB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0003682 - chromatin binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 915
+	Hs
		745164 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		SAFB2_HUMAN (1-906): 1.05e-88: 305: 68.34
+	Hs
		516389 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51
+	Hs
		745179 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBY1F_HUMAN (401-822): 2.17e-37: 149: 18.31
+	Hs
		483431 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBY1A_HUMAN (401-822): 1.22e-36: 147: 18.78
+	Hs
		62458 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		RBY1E_HUMAN (401-822): 1.74e-36: 146: 18.55
+	Hs
		483440 RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74		RBY1F_HUMAN (401-822): 2.17e-37: 149: 18.31
+	Hs
		62459 RBY1E_HUMAN (1-388): 1.16e-33: 132: 49.74		RBY1F_HUMAN (401-822): 2.17e-37: 149: 18.31
+	Hs
		1073368 RBY1F_HUMAN (1-388): 2.31e-33: 131: 49.74		RBY1F_HUMAN (401-822): 2.17e-37: 149: 18.31
+	Hs
		483430 RBY1A_HUMAN (1-388): 1.58e-33: 132: 49.74		RBY1A_HUMAN (401-822): 1.22e-36: 147: 18.78
+	Hs
		516744 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51
+	Hs
		1020249 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PABP4_HUMAN (258-499): 1.89e-40: 161: 15.29
+	Hs
		1047862 CIRBP_HUMAN (4-144): 1.3e-31: 119: 46.00		RBY1F_HUMAN (401-822): 2.17e-37: 149: 18.31
+	Hs
		483438 CIRBP_HUMAN (4-144): 1.3e-31: 119: 46.00		RBY1A_HUMAN (401-822): 1.22e-36: 147: 18.78
+	Hs
		516484 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51
+	Mm
		665745 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		PABP1_MOUSE (258-499): 9.95e-38: 152: 14.51
+	Hs
		1288613 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		PABP5_HUMAN (410-755): 3.8e-25: 110: 11.38
+	Hs
		474019 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PAB4L_HUMAN (407-752): 1.55e-31: 129: 10.08
+	Hs
		198880 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		RFOX2_HUMAN (301-501): 9.17e-31: 127: 21.80