HitPredict

Interactor 1: LSM2 (P38203)
U6 snRNA-associated Sm-like protein LSm2 (Small nuclear ribonucleoprotein D homolog SNP3)
Gene: LSM2

Interactor 2: DHH1 (P39517)
ATP-dependent RNA helicase DHH1 (EC 3.6.4.13) (DExD/H-box helicase 1)
Gene: DHH1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	10688190, 11805837, 26392412, 16429126, 37968396
Identification Methods	two hybrid, anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000932 - P-body GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 95 Sc			1 506
+	Hs
		757543 SMD3_HUMAN (2-88): 1.96e-32: 111: 17.24		IF4A3_HUMAN (10-413): 1.02e-172: 494: 38.42
+	Hs
		757541 SMD1_HUMAN (1-95): 1.45e-26: 95.8: 27.37		IF4A3_HUMAN (10-413): 1.02e-172: 494: 38.42
+	Hs
		757540 RUXF_HUMAN (3-71): 1.74e-21: 82: 34.29		IF4A3_HUMAN (10-413): 1.02e-172: 494: 38.42
+	Hs
		640677 LSM4_HUMAN (1-95): 1.42e-35: 119: 29.90		DDX6_HUMAN (3-421): 1.32e-156: 456: 66.43
+	Sc
		761950 LSM4_YEAST (1-83): 6.06e-25: 93.9: 27.17		DHH1_YEAST (17-506): 2.67e-149: 438: 100.00
+	Hs
		571387 RUXF_HUMAN (3-71): 1.74e-21: 82: 34.29		DDX5_HUMAN (1-417): 2.61e-140: 419: 26.00
+	Dm
		580755 SMD1_DROME (1-94): 9.25e-28: 99.3: 28.72		DDX17_DROME (1-417): 1.21e-129: 395: 27.51
+	Hs
		911887 RUXF_HUMAN (3-71): 1.74e-21: 82: 34.29		DDX42_HUMAN (2-504): 5.03e-130: 402: 23.39
+	Hs
		133961 RUXF_HUMAN (3-71): 1.74e-21: 82: 34.29		DDX3X_HUMAN (2-444): 3.06e-129: 392: 27.08