HitPredict

Interactor 1: LSM2 (P38203)
U6 snRNA-associated Sm-like protein LSm2 (Small nuclear ribonucleoprotein D homolog SNP3)
Gene: LSM2

Interactor 2: LSM1 (P47017)
Sm-like protein LSm1 (SPB8 protein)
Gene: LSM1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.983

Property	Details
Experiments	10747033, 10688190, 10900456, 10428970, 11805837, 11805826, 16429126, 37968396, 16554755, 17513695, 18719247, 19111170, 20108977, 22450758
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, biochemical
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000932 - P-body GO:0005634 - nucleus GO:0005737 - cytoplasm GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 95 Sc			1 172
+	Hs
		167726 LSM2_HUMAN (1-95): 4.64e-40: 129: 63.16		LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22
+	Dm
		1374114 Q9VTW6_DROME (1-95): 9.79e-41: 130: 64.21		Q9W2K2_DROME (36-165): 9.12e-32: 112: 40.00
+	Dm
		1374112 Q9VTW6_DROME (1-95): 9.79e-41: 130: 64.21		Q9W087_DROME (44-136): 1.83e-30: 108: 26.60
+	Hs
		167728 LSM4_HUMAN (1-95): 1.42e-35: 119: 29.90		LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22
+	Hs
		321440 LSM2_HUMAN (1-95): 4.64e-40: 129: 63.16		LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98
+	Dm
		1369698 Q9VKW8_DROME (1-95): 5.35e-36: 120: 26.80		Q9W087_DROME (44-136): 1.83e-30: 108: 26.60
+	Hs
		928046 LSM2_HUMAN (1-95): 4.64e-40: 129: 63.16		RSMN_HUMAN (42-118): 8.26e-24: 95.1: 28.24
+	Hs
		321444 LSM4_HUMAN (1-95): 1.42e-35: 119: 29.90		LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98
+	Hs
		539197 LSM2_HUMAN (1-95): 4.64e-40: 129: 63.16		RSMB_HUMAN (42-118): 3e-23: 93.6: 28.24
+	Hs
		912133 LSM2_HUMAN (1-95): 4.64e-40: 129: 63.16		RUXG_HUMAN (41-117): 5.65e-24: 90.9: 28.57
+	Hs
		1356292 LSM2_HUMAN (1-95): 4.64e-40: 129: 63.16		LSM7_HUMAN (27-117): 7.88e-23: 89: 22.34
+	Hs
		928049 LSM4_HUMAN (1-95): 1.42e-35: 119: 29.90		RSMN_HUMAN (42-118): 8.26e-24: 95.1: 28.24
+	Hs
		539204 LSM4_HUMAN (1-95): 1.42e-35: 119: 29.90		RSMB_HUMAN (42-118): 3e-23: 93.6: 28.24
+	Sc
		746327 LSM2_YEAST (1-95): 4.29e-34: 114: 100.00		LSM7_YEAST (8-119): 4.92e-26: 97.5: 27.97
+	Hs
		1356296 LSM4_HUMAN (1-95): 1.42e-35: 119: 29.90		LSM7_HUMAN (27-117): 7.88e-23: 89: 22.34
+	Dm
		1368675 Q9VKW8_DROME (1-95): 5.35e-36: 120: 26.80		Q9VJI7_DROME (27-119): 5.96e-20: 81.7: 21.65
+	Sc
		746309 LSM2_YEAST (1-95): 4.29e-34: 114: 100.00		LSM8_YEAST (43-150): 4.47e-21: 84.7: 18.52
+	Sc
		746294 LSM2_YEAST (1-95): 4.29e-34: 114: 100.00		RSMB_YEAST (35-153): 5.78e-20: 84: 21.32
+	Sc
		746331 LSM2_YEAST (1-95): 4.29e-34: 114: 100.00		LSM3_YEAST (46-120): 1.16e-19: 80.2: 29.87
+	Sc
		746298 LSM2_YEAST (1-95): 4.29e-34: 114: 100.00		RUXG_YEAST (40-117): 4.06e-19: 78.6: 25.32