HitPredict

Interactor 1: LSM2 (P38203)
U6 snRNA-associated Sm-like protein LSm2 (Small nuclear ribonucleoprotein D homolog SNP3)
Gene: LSM2

Interactor 2: PRP24 (P49960)
U4/U6 snRNA-associated-splicing factor PRP24 (U4/U6 snRNP protein)
Gene: PRP24

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.925

Property	Details
Experiments	10900456, 11805837, 16554755, 11720284, 18971323
Identification Methods	two hybrid, anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LSM~Lsm_interact, LSM~RRM_occluded
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0005688 - U6 snRNP
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 95 Sc			1 444
+	Sc
		767796 LSM4_YEAST (1-83): 6.06e-25: 93.9: 27.17		PRP24_YEAST (1-444): 2.66e-80: 256: 100.00
+	Sc
		376759 LSM2_YEAST (1-95): 4.29e-34: 114: 100.00		PABP_YEAST (2-323): 3.4e-55: 194: 15.39
+	Sc
		376804 LSM4_YEAST (1-83): 6.06e-25: 93.9: 27.17		PABP_YEAST (2-323): 3.4e-55: 194: 15.39
+	Hs
		911843 RUXF_HUMAN (3-71): 1.74e-21: 82: 34.29		SF3B4_HUMAN (22-190): 1.88e-23: 103: 16.58