HitPredict

Interactor 1: LSM2 (P38203)
U6 snRNA-associated Sm-like protein LSm2 (Small nuclear ribonucleoprotein D homolog SNP3)
Gene: LSM2

Interactor 2: SNU66 (Q12420)
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component
Gene: SNU66

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	16429126, 37968396, 21614000
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 95 Sc			1 587
+	Sc
		795438 SMD3_YEAST (2-88): 5.25e-29: 101: 17.24		SNU66_YEAST (1-587): 0: 535: 100.00
+	Sc
		767849 LSM4_YEAST (1-83): 6.06e-25: 93.9: 27.17		SNU66_YEAST (1-587): 0: 535: 100.00
+	Hs
		199850 LSM4_HUMAN (1-95): 1.42e-35: 119: 29.90		SNUT1_HUMAN (4-570): 1.57e-83: 279: 17.44
+	Hs
		199701 RUXF_HUMAN (3-71): 1.74e-21: 82: 34.29		SNUT1_HUMAN (4-570): 1.57e-83: 279: 17.44