HitPredict

Interactor 1: IMB2 (P38217)
Importin subunit beta-2 (Importin-104) (Karyopherin subunit beta-2) (Karyopherin-104) (Transportin) (TRN)
Gene: KAP104

Interactor 2: NUP49 (Q02199)
Nucleoporin NUP49/NSP49 (Nuclear pore protein NUP49/NSP49)
Gene: NUP49

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	9368759
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 918 Sc			1 472
+	Sc
		746520 IMB2_YEAST (1-918): 0: 580: 100.00		NU145_YEAST (1-351): 5.19e-20: 95.7: 16.76
+	Sc
		746533 IMB2_YEAST (1-918): 0: 580: 100.00		NU100_YEAST (1-363): 1.45e-17: 87.9: 20.00
+	Sc
		746518 IMB2_YEAST (1-918): 0: 580: 100.00		NUP57_YEAST (17-256): 3.28e-17: 85.9: 32.67
+	Sc
		746534 IMB2_YEAST (1-918): 0: 580: 100.00		NU116_YEAST (1-276): 9.6e-09: 59.8: 20.85
+	Hs
		858024 TNPO1_HUMAN (1-864): 7.94e-177: 537: 33.03		NUP98_HUMAN (124-327): 9.57e-18: 88.7: 14.67
+	Hs
		834652 TNPO1_HUMAN (1-864): 7.94e-177: 537: 33.03		NU153_HUMAN (1-243): 4.4e-17: 86.7: 18.00
+	Hs
		727300 TNPO1_HUMAN (1-864): 7.94e-177: 537: 33.03		NU214_HUMAN (9-247): 6.29e-16: 82.9: 22.39
+	Hs
		155553 TNPO2_HUMAN (3-862): 2.26e-166: 510: 31.89		NUP98_HUMAN (124-327): 9.57e-18: 88.7: 14.67
+	Hs
		155550 TNPO2_HUMAN (3-862): 2.26e-166: 510: 31.89		NU153_HUMAN (1-243): 4.4e-17: 86.7: 18.00
+	Ce
		248186 O62332_CAEEL (3-863): 1.11e-155: 481: 29.85		Q9XWK3_CAEEL (48-375): 6e-17: 85.2: 18.44
+	Ce
		248176 O62332_CAEEL (3-863): 1.11e-155: 481: 29.85		Q21295_CAEEL (53-210): 4.88e-11: 67.1: 18.45
+	Ce
		248185 O62332_CAEEL (3-863): 1.11e-155: 481: 29.85		Q9U3B9_CAEEL (37-275): 6.81e-10: 63.3: 14.23
+	Tt
		101907 G0SGZ5_CHATD (3-862): 2.36e-138: 438: 28.24		NU145_CHATD (18-328): 2.36e-10: 65.2: 20.67
+	Hs
		857978 IMB1_HUMAN (13-885): 1.66e-97: 327: 11.77		NUP98_HUMAN (124-327): 9.57e-18: 88.7: 14.67
+	Hs
		834599 IMB1_HUMAN (13-885): 1.66e-97: 327: 11.77		NU153_HUMAN (1-243): 4.4e-17: 86.7: 18.00
+	Hs
		727254 IMB1_HUMAN (13-885): 1.66e-97: 327: 11.77		NU214_HUMAN (9-247): 6.29e-16: 82.9: 22.39
+	Sc
		687969 IMB3_YEAST (9-858): 2.92e-90: 311: 15.32		NU145_YEAST (1-351): 5.19e-20: 95.7: 16.76
+	Sc
		687967 IMB3_YEAST (9-858): 2.92e-90: 311: 15.32		NUP57_YEAST (17-256): 3.28e-17: 85.9: 32.67
+	Xl
		853820 IMB_XENLA (13-885): 1.77e-96: 324: 11.44		Q6DCP4_XENLA (1-344): 4.76e-09: 60.6: 18.61
+	Sc
		687954 IMB3_YEAST (9-858): 2.92e-90: 311: 15.32		NU159_YEAST (2-419): 1.68e-10: 65.6: 12.88