HitPredict

Interactor 1: SLT11 (P38241)
Pre-mRNA-splicing factor SLT11 (Extracellular mutant protein 2) (Synthetic lethality with U2 protein 11)
Gene: ECM2

Interactor 2: CWC2 (Q12046)
Pre-mRNA-splicing factor CWC2 (Complexed with CEF1 protein 2) (PRP19-associated complex protein 40) (Synthetic lethal with CLF1 protein 3)
Gene: CWC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 37968396, 11884590, 14690591
Identification Methods affinity chromatography technology, tandem affinity purification, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0017070 - U6 snRNA binding
GO:0036002 - pre-mRNA binding
GO:0071006 - U2-type catalytic step 1 spliceosome
and 1 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 364
Sc

1 339
+ Sp
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024