Interactor 1: TIM23 (P32897)
Mitochondrial import inner membrane translocase subunit TIM23 (Membrane import machinery protein MIM23) (Mitochondrial protein import protein 3) (Mitochondrial protein import protein MAS6)
Gene: TIM23

Interactor 2: TIM21 (P53220)
Mitochondrial import inner membrane translocase subunit TIM21
Gene: TIM21

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 25263020, 15797382, 16943180, 32186971, 18418384, 37527780, 19884344, 23403928, 24061477, 16107694, 15878866, 28011846, 27994013, 30279421, 18400944, 32130909, 25124039, 34588454, 19506038, 22613836
Identification Methods nuclear magnetic resonance, affinity chromatography technology, biochemical, pull down, x-ray crystallography, cross-linking study, surface plasmon resonance, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex
GO:0030150 - protein import into mitochondrial matrix
GO:0045039 - protein insertion into mitochondrial inner membrane
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 222
Sc

1 239
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025