Interactor 1: RFC5 (P38251)
Replication factor C subunit 5 (Replication factor C5) (Activator 1 40 kDa subunit)
Gene: RFC5

Interactor 2: RFC2 (P40348)
Replication factor C subunit 2 (Replication factor C2) (Activator 1 41 kDa subunit)
Gene: RFC2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 11283351, 9710632, 14530260, 8995429, 12390024, 11432854, 16554755, 18719252, 37968396
Identification Methods two hybrid pooling approach, coimmunoprecipitation, pull down, biochemical, affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~DNA_pol3_delta2, DNA_pol3_delta2~Rep_fac_C
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0003677 - DNA binding
GO:0003689 - DNA clamp loader activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 11 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 354
Sc

1 353
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ At
+ Sc
+ Hs
+ Dm
+ Dm
+ Zm
+ Hs
+ Sc
+ Dm
+ Sc
+ Dm

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Last updated: 15 Jul 2024