Interactor 1: SIF2 (P38262)
SIR4-interacting protein SIF2
Gene: SIF2

Interactor 2: HST1 (P53685)
NAD-dependent protein deacetylase HST1 (EC 2.3.1.286) (Homologous to SIR2 protein 1) (Regulatory protein SIR2 homolog 1)
Gene: HST1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.687

The method score is based on:

Property Details
Experiments 11711434, 11805826, 37968396, 16429126
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0006974 - DNA damage response
GO:0009267 - cellular response to starvation
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 535
Sc

1 503
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024