Interactor 1: MED8 (P38304)
Mediator of RNA polymerase II transcription subunit 8 (Mediator complex subunit 8)
Gene: MED8

Interactor 2: MED6 (P38782)
Mediator of RNA polymerase II transcription subunit 6 (Mediator complex subunit 6)
Gene: MED6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.932

The method score is based on:

Property Details
Experiments 9710620, 26240385, 16554755, 16263706, 27688401, 37968396
Identification Methods affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med6~Med8
Common GO terms GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 223
Sc

1 295
+ Ca

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024