Interactor 1: MED8 (P38304)
Mediator of RNA polymerase II transcription subunit 8 (Mediator complex subunit 8)
Gene: MED8

Interactor 2: MED21 (P47822)
Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (RNAPII complex component SRB7) (Suppressor of RNA polymerase B 7)
Gene: SRB7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.703

The method score is based on:

Property Details
Experiments 12468546, 16554755, 16263706, 27688401, 37968396
Identification Methods affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003712 - transcription coregulator activity
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
and 6 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 223
Sc

1 140
+ Ca

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Last updated: 15 Jul 2024