Interactor 1: MED8 (P38304)
Mediator of RNA polymerase II transcription subunit 8 (Mediator complex subunit 8)
Gene: MED8

Interactor 2: MED7 (Q08278)
Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7)
Gene: MED7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 11805826, 16263706, 27688401, 37968396, 9420330, 16429126, 16962561, 26317468, 28575439, 15356001
Identification Methods tandem affinity purification, biochemical, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med7~Med8
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 223
Sc

1 222
+ Ca
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024