Interactor 1: DER1 (P38307)
Degradation in the endoplasmic reticulum protein 1
Gene: DER1

Interactor 2: HRD1 (Q08109)
ERAD-associated E3 ubiquitin-protein ligase HRD1 (EC 2.3.2.27) (HMG-CoA reductase degradation protein 1) (RING-type E3 ubiquitin transferase HRD1)
Gene: HRD1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.55 0.702

The method score is based on:

Property Details
Experiments 16873066, 35970394, 20005842, 16619026, 18407841, 24292014
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000836 - Hrd1p ubiquitin ligase complex
GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005789 - endoplasmic reticulum membrane
GO:0030968 - endoplasmic reticulum unfolded protein response
GO:0030970 - retrograde protein transport, ER to cytosol
and 1 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024