HitPredict

Interactor 1: ATG12 (P38316)
Ubiquitin-like protein ATG12 (Autophagy-related protein 12)
Gene: ATG12

Interactor 2: ATG7 (P38862)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (Cytoplasm to vacuole targeting protein 2)
Gene: ATG7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.750

The method score is based on:

Property Details
Experiments 10233150, 10688190, 11283351, 11139573, 37894717, 12965207, 38057553
Identification Methods two hybrid, two hybrid pooling approach, coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000045 - autophagosome assembly
GO:0000422 - autophagy of mitochondrion
GO:0005829 - cytosol
GO:0006501 - C-terminal protein lipidation
GO:0016236 - macroautophagy
and 3 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 186
Sc

1 630
+ Hs
+ Mm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024