Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1
Interactor 2: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.97 | 1.00 | 0.990 |
The method score is based on:
Property | Details |
---|---|
Experiments | 25184681, 14578343, 11573086, 9525870, 26778126, 27977889, 27312108, 29180510, 29656893, 29899443, 25091198, 32092106, 29367421, 16543155, 34591612, 16818604, 20351172, 21965653, 11927591, 21880590 and 5 others
more... |
Identification Methods | affinity chromatography technology, unspecified method, x-ray crystallography, pull down, enzymatic study, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | BRCT~BRCT |
Common GO terms | GO:0000151 - ubiquitin ligase complex GO:0000152 - nuclear ubiquitin ligase complex GO:0000724 - double-strand break repair via homologous recombination GO:0000800 - lateral element GO:0000931 - gamma-tubulin ring complex and 71 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024