HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: TXLNA (P40222)
Alpha-taxilin
Gene: TXLNA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25184681
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1863 Hs			1 546
+	Hs
		148473 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		CTRO_HUMAN (53-490): 8.24e-10: 63.8: 13.93
+	Hs
		551628 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		DESP_HUMAN (55-506): 1.98e-09: 62.8: 11.92
+	Hs
		531606 TRI58_HUMAN (16-390): 3.39e-69: 243: 12.53		K2C5_HUMAN (158-515): 2.6e-45: 170: 16.26
+	Hs
		318774 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		K2C75_HUMAN (158-519): 8.16e-43: 162: 16.62
+	Hs
		536787 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		K22O_HUMAN (158-519): 4.16e-38: 150: 17.16
+	Hs
		517736 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		K2C3_HUMAN (158-503): 1.35e-36: 145: 16.25
+	Hs
		380469 TRI26_HUMAN (12-287): 2.53e-51: 193: 14.53		K2C6B_HUMAN (158-522): 3.39e-46: 172: 16.22
+	Hs
		821686 TRIM7_HUMAN (19-291): 1.53e-44: 172: 12.16		K2C6C_HUMAN (158-521): 4.48e-46: 171: 16.80
+	Hs
		522639 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH7_HUMAN (7-546): 5.06e-15: 80.7: 9.65
+	Hs
		729168 TRIM7_HUMAN (19-291): 1.53e-44: 172: 12.16		K22E_HUMAN (159-507): 3.82e-32: 132: 16.39
+	Hs
		536947 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		RBCC1_HUMAN (166-470): 7.27e-09: 60.7: 21.52
+	Hs
		528393 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		MYH6_HUMAN (1-414): 3.64e-10: 64.9: 10.60
+	Hs
		585020 RO52_HUMAN (15-390): 2.55e-68: 241: 12.86		RBCC1_HUMAN (166-470): 7.27e-09: 60.7: 21.52
+	Hs
		531626 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		K2C5_HUMAN (158-515): 2.6e-45: 170: 16.26
+	Hs
		1062065 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		K2C72_HUMAN (159-508): 3.29e-45: 168: 15.24
+	Hs
		149258 TRIM4_HUMAN (15-377): 1.5e-62: 225: 11.52		CTRO_HUMAN (53-490): 8.24e-10: 63.8: 13.93
+	Hs
		1255682 TRIM5_HUMAN (10-339): 1.37e-63: 227: 13.27		RBCC1_HUMAN (166-470): 7.27e-09: 60.7: 21.52
+	Hs
		1255683 TRIM4_HUMAN (15-377): 1.5e-62: 225: 11.52		RBCC1_HUMAN (166-470): 7.27e-09: 60.7: 21.52
+	Hs
		1169848 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		WDR87_HUMAN (118-488): 1.28e-33: 138: 15.53
+	Hs
		729167 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		K22E_HUMAN (159-507): 3.82e-32: 132: 16.39