Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 32814053
Identification Methods two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0032991 - protein-containing complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1863
Hs

1 3142
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024