HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26831064
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 545
+	Hs
		749818 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Hs
		749217 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		573154 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		749243 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Hs
		826712 TRI68_HUMAN (12-388): 1.67e-74: 259: 11.31		TCPG_HUMAN (1-545): 0: 640: 100.00
+	Hs
		821319 MCPH1_HUMAN (1150-1857): 1.33e-95: 331: 14.19		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		1149902 TRI68_HUMAN (12-388): 1.67e-74: 259: 11.31		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Hs
		821263 TRI68_HUMAN (12-388): 1.67e-74: 259: 11.31		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		573310 TRI68_HUMAN (12-388): 1.67e-74: 259: 11.31		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		843245 TRI68_HUMAN (12-388): 1.67e-74: 259: 11.31		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Hs
		843371 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56