Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1
Interactor 2: BRCA2 (P51587)
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
Gene: BRCA2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.759 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11477095, 14499622, 19369211, 25184681, 25652403, 14636569, 29656893, 9774970, 34408138, 21135251, 17664283, 24085845 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, biochemical, proximity labelling technology, anti bait coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000152 - nuclear ubiquitin ligase complex GO:0000724 - double-strand break repair via homologous recombination GO:0000800 - lateral element GO:0005634 - nucleus GO:0005654 - nucleoplasm and 6 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
