HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 0.60 0.672

The method score is based on:

Property Details
Experiments 25084169, 26831064, 10783165, 29656893
Identification Methods affinity chromatography technology, biochemical, proximity labelling technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0000800 - lateral element
GO:0002039 - p53 binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
and 10 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1863
Hs

1 1417
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024