HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	26831064, 22990118
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 814
+	Hs
		749840 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		TBL1R_HUMAN (408-730): 1.7e-53: 195: 11.90
+	Hs
		749312 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Hs
		1266889 TOPB1_HUMAN (1122-1861): 3.79e-150: 505: 14.12		NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03
+	Hs
		903462 BARD1_HUMAN (13-366): 4.46e-32: 137: 11.98		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71