HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: KIF23 (Q02241)
Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)
Gene: KIF23

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26831064, 29656893
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 960
+	Hs
		231466 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		KIF1B_HUMAN (22-927): 1.18e-124: 418: 16.49
+	Hs
		308465 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		KI20A_HUMAN (19-843): 9.36e-121: 391: 23.80
+	Hs
		749267 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		KIF11_HUMAN (10-711): 1.83e-114: 378: 19.63
+	Hs
		749697 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		KI18A_HUMAN (16-698): 2.02e-103: 345: 16.59
+	Hs
		749791 BRCA1_HUMAN (1-1863): 0: 1570: 100.00		KI20B_HUMAN (23-438): 3.71e-53: 204: 34.54
+	Hs
		536789 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		KIF23_HUMAN (1-960): 0: 670: 100.00
+	Hs
		308371 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		KI20A_HUMAN (19-843): 9.36e-121: 391: 23.80
+	Hs
		536804 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		KIF1A_HUMAN (23-770): 2.14e-113: 385: 16.60
+	Hs
		309041 TRIM5_HUMAN (10-339): 1.37e-63: 227: 13.27		KI20A_HUMAN (19-843): 9.36e-121: 391: 23.80
+	Hs
		309042 TRIM4_HUMAN (15-377): 1.5e-62: 225: 11.52		KI20A_HUMAN (19-843): 9.36e-121: 391: 23.80
+	Hs
		855729 TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54		KIF11_HUMAN (10-711): 1.83e-114: 378: 19.63
+	Hs
		309040 TRIM7_HUMAN (19-291): 1.53e-44: 172: 12.16		KI20A_HUMAN (19-843): 9.36e-121: 391: 23.80