Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1
Interactor 2: RAD51 (Q06609)
DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)
Gene: RAD51
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25499220, 28976962, 17302439, 9008167, 25659039, 14636569, 11498787, 29656893, 9774970, 34408138, 31270457 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, biochemical, far western blotting, proximity labelling technology |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000152 - nuclear ubiquitin ligase complex GO:0000724 - double-strand break repair via homologous recombination GO:0000800 - lateral element GO:0001673 - male germ cell nucleus GO:0005634 - nucleus and 8 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
